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TB-500

Thymosin Beta-4 · 10mg vial
A$ 151Rp 1.700.000
Bulk buy pricing
3–5 vials
A$ 138
Save ~9%
6–9 vials
A$ 133
Save ~13%
10+ vials
A$ 120
Save ~22%

A regenerative compound studied for tissue repair across the body — helping cells move to where they are needed for healing. Research supports its use for soft-tissue and tendon recovery, inflammation reduction, and broader healing support.


Compound overview

What it is

TB-500 is a synthetic version of the naturally occurring peptide Thymosin Beta-4, one of the most abundant actin-sequestering proteins in the body. It upregulates actin polymerisation and promotes cell migration — enabling repair cells (satellite cells, myoblasts, endothelial cells) to move toward sites of damage. It also promotes angiogenesis, reduces inflammation, and supports cardiac tissue recovery. Unlike BPC-157, which acts on specific tissue types, TB-500 acts systemically via cellular migration.

Healing mobilisation accelerates system-wide. Injured muscle, tendon, skin, and cardiac tissue all show accelerated recovery in studies. Inflammation at injury sites reduces. Flexibility may improve as connective tissue remodels. Effects are not limited to a single anatomical site — cells travel through the circulation to sites of damage throughout the body.

Studied outcomes
  • Accelerated skeletal muscle repair in injury and denervation models
  • Cardiac tissue recovery following ischaemic injury in animal studies
  • Improved hair follicle cycling and wound healing
  • Angiogenesis and vascular repair across multiple tissue types
  • Reduced inflammatory cytokine expression at injury sites

Suitability

Who it's for

  • Systemic injury recovery — multiple sites or whole-body healing
  • Muscle tears, tendon injuries, and post-surgical tissue repair
  • Inflammation-driven chronic injuries
  • Pairing with BPC-157 for a complete recovery stack
Who should avoid it
  • Active cancer — angiogenic and cell migration activity
  • Pregnancy
  • Those seeking a targeted, local tissue effect only (BPC-157 may be more appropriate)

Dosing guidance

Protocol guidance

Dose
2.0–2.5mg per week loading dose; 1.0–1.5mg per week maintenance
Frequency
Twice weekly injections
Cycle length
4–6 week loading phase, followed by maintenance; 8–12 weeks total
Route
Subcutaneous or intramuscular injection
Timing
No strict timing requirement

Safety

Contraindications & cautions

  • Angiogenic activity — theoretical concern in those with active or recent malignancy
  • Well-tolerated in clinical use; minimal reported adverse effects
  • Best combined with adequate protein intake and rehabilitation
  • Do not confuse with Thymosin Alpha-1 — different compound, different mechanism

Stacking

Pairs well with

Canonical recovery stack — local connective tissue repair (BPC-157) + systemic cellular migration (TB-500)

Anti-inflammatory support complements the regenerative action of TB-500

GH secretagogues amplify anabolic recovery; TB-500 handles tissue mobilisation


Evidence base

Research

Goldstein et al. (2005) — Thymosin Beta-4 and actin sequestration reviewSmart et al. (2007) — Thymosin Beta-4 and cardiac regeneration

Not medical advice. Not a substitute for medical care. Consult your licensed practitioner before beginning any protocol. Peptides are sold for research purposes only and are suitable for adults aged 18 years and over.